Volatiles Constituents and Anticonvulsant Activity of the Aerial Parts of Dichrostachys Cinerea L

AH, Abou; MS, Hifnawy; RS, Mohammed; Sleem, Amany A.

doi:10.21608/sjou.2014.32952

Volatiles Constituents and Anticonvulsant Activity of the Aerial Parts of Dichrostachys Cinerea L

Document Type : Original Article

Authors

¹ Pharmacognosy and Pharmacology Departments, National Research Centre, El-Tahrir St., Dokki, 12622 , Cairo, Egypt

² Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr Al-Aini St, 11562, Cairo, Egypt

10.21608/sjou.2014.32952

Abstract

GC/MS analysis of the volatile constituents of aerial parts of D. cinerea revealed the identification of 70 compounds representing (86.13%) of the total volatiles of the plant. α-Pinene (26.47%), nonanal (5.11%) and 8, 11, 14 eicosatrienoic acid (4.90%) were found to be the major compounds. Oxygenated compounds constituted (32.81%) mainly attributed to nonanal (5.11%), 8, 11, 14 eicosatrienoic acid (4.90%), hexadecanoic acid (2.95%), phytol (1.17%), β-ionone (1.45%), and methylisoeugenol (1.08%). Anticonvulsant activity of the total ethanol extract and successive extracts were investigated which revealed that highest activities were exhibited after 2 hours by100mg of total ethanol extract (80.87% potency), methanol extract (121.76% potency) and 100mg of ethyl acetate extract (74.15% potency) respectively

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